Significant projects

Application Laboratories of Advanced Microtechnologies and Nanotechnologies

The aim of ALISI is to build and run a modernly equipped research center that achieves the applicable research and development results, bringing the technological level of local research and development in the areas of the world elite. The existence of the Center is a new impetus for expanding cooperation with domestic and foreign industrial partners, universities, health institutes and research institutions. More information: alisi.isibrno.cz

ALISI - Advanced Diagnostic Methods and Technologies Center - NPU

The "ALISI - Advanced Diagnostic Methods and Technologies" project is supported by the National Program of Sustainability I-NPU I (LO), which aims to support research, experimental development and innovation from public funds.

Czech-BioImaging

Czech-BioImaging is a national research infrastructure for biological and medical imaging. It is a distributed infrastructure of leading imaging facilities in the Czech Republic. The infrastructure provides an open access to a wide range of imaging technologies and expertise to all scientists in the Czech Republic and from abroad by a unified and coordinated logistics approach.
The aim of Czech-BioImaging is:

to enable a permanent access to cutting edge imaging technologies and expertise in imaging to scientists, which do not have available at their own institutions,
to increase awareness and knowledge of biological and medical imaging,
to support mutual cooperation of scientists and sharing of best practices and knowledge.

The Core Facility Magnetic Resonance (ISI-MR) and the Core Facility Electron Microscopy and Raman Spectroscopy (ISI-EM) at the Institute of Scientific Instruments of the CAS provide support to academic institutions and industrial companies in their basic research and development of more effective therapies or diagnostic markers. Application needs and client feedback provide important stimuli for in-house research and development of measurement techniques available in laboratories. This research is carried out by members of the laboratory teams within their affiliation to research groups according to their focus (Magnetic Resonance, Microscopy for Biomedicine, Microscopy and Microanalysis, Biophotonics and Optofluidics). Access to the services of the laboratories is supported by their inclusion in the Czech-BioImaging and Euro-BioImaging networks, which contribute to the funding of the operation and provide expert feedback to put pressure on the high quality of the service.

Core Facility Magnetic Resonance (ISI-MR)

Core Facility Electron Microscopy and Raman Spectroscopy (ISI-EM)

Laser length sensors for diagnostics of geometric dimensions and surface defects in precision engineering

The new generation of super precision digital automated machines in the automotive industry enables the machining of precision machining products up to the nanometer range.
However, to ensure the highest degree of reliability, this accurate production requires a 100% accuracy check.
The aim of the project is to research and develop unique optical methods that allow automated production lines to measure the geometric dimensions of engineering products with a resolution approaching the nanometer boundary.
Financial support from the European Union is provided for the operation.

High - tech detection systems for electron microscopy

This is a project from the OP Entrepreneurship and Competitiveness Innovation 2014-2020, the priority axis of the Operational Program PO-1 "Development of Research and Development for Innovations", the name of the support program Application, challenge I.
High-tech high-tech scintillation and scintillation ionization detectors of scanning electrons for scanning and environmental scanning electron microscopes will be tested and developed using mathematical-physics modeling and Monte Carlo simulations and the sharing of cutting-edge technologies and know-how. The results of the project, characterized by high technological level and high added value, build on experience and efficient academic and corporate cooperation and are designed for the global market.
Financial support from the European Union is provided for the operation.

Advanced technology for non-invasive cardiac electromechanical diagnostics - VDI monitor

The project includes industrial research and experimental development of new medical technology designed for non-invasive diagnostics of cardiac electro-mechanical disorders.
The output of the project is the original Ventricular Dyssynchrony Imaging (VDI) device using ultra-high frequency ECG recording.
VDI is primarily designed for the diagnosis of heart failure and serious heart disease. Completely new VDI technology can be a major breakthrough in the diagnosis of heart disease.

Financial support from the European Union is provided for the operation.

Application of advanced interferometric methods for measuring surfaces in optical production

This is a project from the OP Entrepreneurship and Competitiveness Innovation 2014-2020, the priority axis of the Operational Program PO-1 "Development of Research and Development for Innovations", the name of the support program Application, challenge I.
The project will focus on the implementation of advanced interferometric methods for measurement in optical production. In its implementation, industrial research, experimental development will be carried out, including testing of interferometric devices for two types of measurements in the optical manufacturing process. Emphasis will also be put on the research and development of methods eliminating the impact of environmental conditions on interferometric measurements on an existing interferometric device.

Financial support from the European Union is provided for the operation.

Calibration of optical sensor systems and special sensors for nuclear power plants

The project is focused on the research of internal and external laser calibration of the system for monitoring the state of finished civil engineering works.
The pilot system with internal and external calibration module will be applied in the system for measuring the shape changes of the Temelín NPP containment.
Internal references in the system will allow it to function continuously even if the system is disconnected from external sources. External will allow for periodic remote calibration, which will be directly related to the baseline normals.

Financial support from the European Union is provided for the operation.

Holographic endoscopy for in vivo applications

Short project title: Gate2µ (Gate2mu)
The registration number: CZ.02.1.01/0.0/0.0/15_003/0000476

This is a project from the OP Research, Development and Training, call Support excellent research teams in priority axis 1 OP - Strengthening the capacity for quality research.

The project will bring together an international team of experts from a variety of scientific fields, who will develop endoscopic probes with the thickness of a human hair, allowing super-resolved observations and further contemporary qualities of the most advanced imaging approaches. The developed technology will provide a unique insight into living awake and motile animal models and ultimately human organs.

This project is co-financed by the EU.

The main project presentation are here.

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Quantum-Classical Ultimate Turbulence Analogies in Heat

The project synergicaly connects theoretical and experimental research into ultimate regimes of transport of heat by turbulent flows of classical and quantum fluids at cryogenic temperatures. The aims are (i) to formulate a unfied model describing the heat trasnfer laws in quantum fluid (superfluid helium-4, in the so-called "quantum counterflow") and in a classical fluid (normal gaseous helium-4 in the Rayleigh-Benard convection), (ii) development of a novel and potentially groundbreaking experimental method of flow field visualisation, using laser-induced fluorescence of long-lived metastable molecular excimers He_2*, suitable for both the classical and quantum flow.
Financial support from the European Union is provided for the operation.